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Science Sparks @ ACTREC
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 15th September 2025 |
Vol. No. 14 ; Issue No.700 |
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Publications
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1. Chaudhary N, Mandal D, Choudhary B, Patra S, Jain D, Poonia P, Shaikh S, Tekalkar S, Malvankar S, Shivashankar A, Jog E, Pilankar L, Thorat R, Kailje V, Khanna S, Manna S, Khan B, Jadhav A, Sharma K, Ramu S, Sahoo S, Jolly MK, Dalal SN, Sinha S, Nair N, Ruppin E, Lamballe F, Maina F, Verma N (2025).Low-GPX4 drives a sustained drug-tolerant persister state in TNBC by a targetable adaptive FSP1 upregulation. Redox Biology.
2. Rajput NH (2025). The digital shift in oncology EMRs in LMICs. ESMO Real World Data and Digital Oncology. 10:100183.
3. Bagdiya P, Soni N, Jaiswal D, Dalvi S, Kanitkar T, Madhusudhan MS, Venkatraman P (2025). ATP-driven allosteric regulation of 14-3-3: positive modulation of ATP hydrolysis and negative regulation of peptide binding. FASEB Journal.39(18):e70985.
4. Keshari R, Bagale R, Rath S, Raut S, Bhatt LK, De A, Sen S, Srivastava R (2025). Soya lecithin–PLGA based hybrid nanocomposite enhances resveratrol delivery for psoriasis treatment and management. Industrial Crops and Products.236:121575
Patent
Kode J, Mathen C (2025). Immune modulating therapy using UC-MSC-CM to inhibit tumor growth. (Indian Patent Number: 570565)
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Interesting Reads
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Dehingia B, Milewska-Puchała M, Janowski M, Rafiee MR, Abbas M, Piotrowska A, Senge J, Blaut P, Walsh D, Severino J, Chaudhury D, Iqbal S, Montiel-Manriquez R, Jankowska S, Zare P, Huber W, Xu J, Casellas R, Zimmermann T, Dłotko P, Krijgsveld J, Pękowska A (2025). RNA-binding proteins mediate the maturation of chromatin topology during differentiation. Nature Cell Biology.
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Video of the Week
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| Restoring the Core Logic of Randomization to Avert Common Pitfalls in Biopharmaceutical Statistics |
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Do You Know?
In 2012, Vismodegib (Erivedge) was the first drug approved for basal cell carcinoma, the most common type of skin cancer.
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Cancer News
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New multi-disciplinary approach sheds light on the role of mitochondrial DNA mutations in cancer
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Eurekalert, 10/09/2025
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While this research highlights the role mitochondrial DNA mutations might play in leukemia, the main achievement is the creation of a novel multidimensional approach to investigate mtDNA. Kundu is optimistic about the value of digging deeper into this overlooked feature of cancer growth...
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Blocked blood flow makes cancer grow faster
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Sciencedaily, 11/09/2025
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Researchers discovered that cutting off blood flow accelerates cancer growth by prematurely aging the bone marrow and weakening the immune system. In mouse models, restricted blood flow doubled the growth rate of breast tumors, mimicking changes seen during aging...
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2025 Advanced Centre for Treatment, Research and Education in Cancer (ACTREC)
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